Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, Fogo A, Niimura F, Ichikawa I, Hogan BL, Inagami T. Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II
In sheep, placental size is maximal by midgestation, but blood flow continues to increase until term. No nerves are present and ANG II is thought to be a major regulator of vascular
Miyazaki R, Ichiki T, Hashimoto T, et al. SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells. Arterioscler Thromb
In both cases the AMA were demonstrated to be maternal in origin, as in both infants they were of the placenta-crossing IgG1 and IgG 3 class, their concentrations declining over several weeks . The epitope recognition pattern was also the same in both infant].
The expression of brown/beige adipocyte marker genes was first analyzed to determine whether beige adipocytes were induced by DHA treatment in 3T3-L1 cells. As expected, the mRNAs levels of brown/beige adipocyte-specific genes, namely UCP1, Tnfrsf9, Cited1, Eva1a, and PDK4, were significantly increased in the DHA-treated 3T3-L1 cells compared to the control group (Figure 1A).
Transforming growth factor-beta (TGF- β ) is a pleiotropic factor, with several different roles in health and disease. TGF- β has been postulated as a dual factor in tumor progression, since it represses epithelial tumor development in early
Evidence sustains a role for the acute-phase protein serum amyloid A (SAA) in carcinogenesis and metastasis, and the protein has been suggested as a marker for tumor progression. Nevertheless, the demonstration of a direct activity of SAA on tumor cells is still
The expression of adrenomedullin in the cytotrophoblast was most abundant in first trimester placenta and became less abundant during the course of pregnancy. JAr cells synthesized and secreted immunoreactive adrenomedullin. Binding assay with [125I]rat
血管紧张素_受体及其受体阻滞剂的研究进展_医药卫生_专业资料 744人阅读|101次下载 血管紧张素_受体及其受体阻滞剂的研究进展_医药卫生_专业资料。 28 J Med Theor ＆Prac Vol．25，No．1，Jan 2012 2012 年 第25 卷 第1 期 医学理论与实践 血管紧张素Ⅱ受体及其受体阻滞剂
Then chewing them with a crunching noise, she blew them away, and from the true-mist of her breath Gods were born. The first was named Ta-gori-bime, the next Tagi-tsu-bime, and the next Ichiki-shima-bime, three daughters in all.
Two G protein–coupled receptors (GPCRs) have been cloned as receptors for leukotriene B 4 (LTB 4) (Table 1 and refs. 8, 9).The first, BLT 1, known as a high-affinity LTB 4 receptor, is expressed in various subsets of leukocytes and is responsible for LTB 4-dependent
Isobutyryl-L-carnitine is a member of the class of compounds known as acyl carnitines. Acyl carnitines are organic compounds containing a fatty acid with the carboxylic acid attached to carnitine through an ester bond. Isobutyryl-L-carnitine is practically
Dictionaries ( DICCIONARIO BÁSICO ILUSTRADO WAYUUNAIKI-ESPAÑOL ESPAÑOL-) DICCIONARIO BÁSICO ILUSTRADO WAYUUNAIKI-ESPAÑOL ESPAÑOL-WAYUUNAIKI
The purpose of our present study is to identify a tumor-specific antigen capable of inducing a specific cellular immune response in lung cancer patients. We established a lung adenocarcinoma cell line, designated as F1121L, and induced tumor-specific CTL clone
Quantitative distribution of corticosteroids in three placenta analyzed here showed a marked individual difference but in all the placental tissues analyzed, the content of 11-deoxycorticosterone and 11-dehydrocorticosterone was higher than that of the three kinds
Abstract Collectrin, a novel homolog of angiotensin-converting enzyme-related carboxypeptidase (ACE2), was identified during polymerase chain reaction-based cDNA subtraction and up-regulated in 5/6 ablated kidneys at hypertrophic phase.
Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate studies and therapies as powerful tools for drug delivery, monitoring of specific analytes, and medical diagnostics. Most remarkably
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The causes of mid-pregnancy bleeding are less well understood. In one study, two-thirds of the cases were found to be due to premature separation, placenta praevia, hydatiform moles, incompetent cervices, and other identifiable causes, while in one-third of the.
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via
PROBLEM TO BE SOLVED: To provide new melanogenesis inhibitor composition that has a sufficient fair skin effects, namely effectively inhibits and ameliorates the skin dyspigmentation, for example, chloasma, freckle, dark spots or melanodermatitis caused
General Comments The ATGR2 appears to be re-expressed or up-regulated after vascular injury, myocardial infarction, cardiac failure or wound healing, possibly reflecting re-activation of a foetal genetic programme [18-19,36,56] Preclinical in vitro and in vivo studies indicated that the AT 2 receptor counterbalances the effect of the AT 1 receptor [18,56,60,62-63].
Read “Immunohistochemical adrenomedullin expression is decreased in the placenta from pregnancies with pre‐eclampsia, Pathology International” on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications
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Early-life origins of schizotypal traits in adulthood – Volume 195 Issue 2 – Jari Lahti, Katri Räikkönen, Ulla Sovio, Jouko Miettunen, Anna-Liisa Hartikainen, Anneli Pouta, Anja Taanila, Matti Joukamaa, Marjo-Riitta Järvelin, Juha Veijola
PPARγ is a transcriptional factor regulating the expression of multiple genes, hence promoting the differentiation and development of various tissues, specifically in adipose tissue, brain, placenta, and skin. Interestingly, neuroprotective effects of PPARγ agonist).
Silk Protein Enzyme Degradation Solution 1.0 19.Pig placenta water extract 1.0 20. Antibacterial and antiseptic (paraoxybenzoic acid ester) appropriate amount 21. The balance of 100 purified water (Formulation Example 3) Cosmetic Oil Mass% 1.liquid 5.
Human Cardiac Fibroblasts (HCF) are the most prevalent cell type in the heart. HCF from Cell Applications, Inc. provide an excellent model system to study many aspects of
The midgestational maternal blood pressure (BP) decrease is absent in mice treated with an angiotensin II AT2 receptor blocker. We tested the hypotheses that there would be 1
Clinical evaluation of CENP‑B and Scl‑70 autoantibodies in silicosis patients Suni Lee, Hiroaki Hayashi, Naoko Kumagai‑Takei, Hidenori Matsuzaki, Kei Yoshitome, Yasumitsu Nishimura, Kozo Uragami, Masayasu Kusaka, Shoko Yamamoto, Miho Ikeda, Tamayo Hatayama, Wataru Fujimoto, Takemi Otsuki
10/10/2018 · Experiment Type Center Ames Research Center (ARC) Glenn Research Center Johnson Space Center (JSC) Kennedy Space Center (KSC) NASA Marshall Space Flight Center NSBRI PREPHASE1 At least one field must be filled in.
Molecular Characterization AT 2 receptors have been cloned and characterized in a variety of species, including humans (91, 147), rats, and mice.Expression cloning from a rat pheochromocytoma (PC12W) cell library and a rat fetus library resulted in identification of the rat AT 2 receptor cDNA, which consists of a 1089 bp open reading frame.
Adrenomedullin (AM) is a regulatory peptide whose involvement in tumour progression is becoming more relevant with recent studies. AM is produced and secreted by the tumour cells but also by numerous stromal cells including macrophages, mast cells, endothelial cells, and vascular smooth muscle cells. Most cancer patients present high levels of circulating AM and in some cases these higher
Europe PMC is an archive of life sciences journal literature. Find the latest peer-reviewed research articles and preprints on Coronavirus here.
An autoimmune disease is characterized by tissue damage, caused by self-reactivity of different effector mechanisms of the immune system, namely antibodies and T cells. All autoimmune diseases, to some extent, have implications for fertility and obstetrics.
Dual role of angiotensin II in the human endometrium Human Reproduction, Oct 1996 Xiao-Feng Li, Asif Ahmed Xiao-Feng Li Asif Ahmed Angiotensin II (ANG) promotes cell proliferation and angiogenesis as well as being a potent endometrium has yielded useful
Neuropeptide W (NPW) and neuropeptide B (NPB) are two structurally and functionally related regulatory peptides, which are highly expressed in several brain regions and, additionally, in some peripheral tissues. Nevertheless, their distributions in the tissues are not
D2 is located in the endoplasmic reticulum and is very active in the placenta, cardiac muscle and pituitary gland, where it helps to mediate the TSH production negative feedback loop (26, 27). D1 is found in the plasma membrane of various cells and also25, 26).
In addition, immune-privileged sites such as the placenta, testis, ovary, and eye express high levels of PI-9. 32 Perforin/granzyme-expressing adaptive T regulatory cells may also play an important role in autoimmunity, as suggested by an experimental 33 34
AbstractThe early detection of perinatal brain damage in preterm and term newborns (i.e. intraventricular hemorrhage, periventricular leukomalacia and perinatal asphyxia) still constitute an unsolved issue. To date, despite technological improvement in standard
Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on ‘small’ chemical compounds. 2nd January 2020, Nitrogen dioxide Air pollution is a global health risk that is responsible for millions of premature deaths each year.
O aumento das perdas de iodo pela urina, a passagem deste através da placenta para o feto e a desiodização das hormonas tiroideias na placenta, implica que as necessidades de iodo durante a gravidez aumentem. Se não há iodo suficiente para a produção
Suppressive effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on vascular remodeling that takes place in the normal labyrinth zone of rat placenta during late gestation. Toxicol Sci 91:265-274 16495355. Crossref, Medline, Google Scholar Johnson L, Dickerson R, Safe
Introduction Studies have been conducted in an attempt to identify the genes causing hypertension using 2 strains of hypertensive rats: spontaneously hypertensive rats (SHRs) and a substrain derived from the SHRs, stroke-prone SHRs (SHRSP) (1,2).Normotensive
Sepsis is defined as an exaggerated, systemic inflammatory response to infection and is a common condition in horses. Systemic inflammatory response syndrome (SIRS) associated with bacterial infection is a hallmark of sepsis. Sepsis in neonatal foals is a
We previously reported that survivin-2B, a splicing variant of survivin, was expressed in various types of tumors and that survivin-2B peptide might serve as a potent immunogenic cancer vaccine. The objective of this study was to examine the toxicity of and to c linically and immunologically evaluate survivin-2B peptide in a phase I clinical study for patients with advanced or recurrent breast
Abstract Corin is a membrane-bound protease essential for activating natriuretic peptides and regulating blood pressure. Human corin has 19 predicted N-glycosylation sites in its extracellular domains.It has been shown that N-glycans are required for corin cell surface expression and zymogen activation.
Estriol levels can be measured to give an indication of the general health of the fetus. DHEA-S is produced by the adrenal cortex of the fetus. This is converted to estriol by the placenta. If levels of “unconjugated estriol” are abnormally low in a pregnant woman
It is important to begin reducing your baby’s exposure to chemicals and toxins while they are still in the womb, by reducing your own exposure. Here are three easy ways to reduce
86 Homo sapiens ACBP Acyl-CoA-binding protein 3525533# Marquardt H., Todaro G.J., Shoyab M.; # “Complete amino acid sequences of bovine and human endozepines. 52 Homo sapiens Adrenomedullin Adrenomedullin 8387282# Kitamura K., Kangawa K